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Robotic pharmacist mixing chemo drugs at U.S. hospital

Colorado hospital will be the first in the U.S. to use the robot

By Sharon Gaudin
January 11, 2008 12:00 PM ET

Computerworld - The University of Colorado Hospital is about to start using a robot to mix chemotherapy drugs for patients, which its developers say will eliminate human error and protect technicians from potentially dangerous drugs.

This is the first time the chemotherapy compounding robot will be used in the U.S., according to Shawn Riley, vice president of Primus Innovations Inc.,  which is collaborating with robot developer Health Robotics to distribute the technology. He noted that the technology is being used in Europe.

"The robot eliminates calculation errors," said Nancy Stolpman, director of pharmacy at the University of Colorado Hospital in Denver,  which administers chemo to 80 to 100 patients per day. "[Mistakes] happen. Pharmacists and technicians are no different than any other human. They make errors. Just one decimal point [off in calculation] can be a tenfold overdose for a patient. It can be very dangerous," she said.

And Stolpman, whose organization is set to begin using the robot this month, said she's quite confident that the stationary machine can accurately read the orders for the chemo, which often are a mixture of several different drugs. The machine uses its robotic arm to mix the compounds and deposit them in IV bags, vials or syringes. The robot then drops any articles, like used vials and syringes that are no longer needed or contaminated, into a waste container, so technicians never touch them. The machine even alerts someone when the waste container is nearing full and then closes and seals it.

Riley said the robot, which is called CytoCare, is a third-generation machine. About 50 CytoCare robots have been sold worldwide to date, he said.

Stolpman said they've been testing the robot and have really run it through its paces. "We've tried to get it to make something wrong, and we can't trick it," she added. "It adds several safety checks."

She explained that the machine weighs the drugs before and after they're mixed to confirm the dosage, and it checks bar codes on the drug packaging to make sure it has the right drug. To double check that, the machine places the drug on a platform and rotates it 360 degrees, taking images of the drug and comparing those to images stored in its database. "It knows what it should look like, and it will reject it if it doesn't match," said Stolpman. "I think we definitely need the extra safety checks."

And that added layer of safety also protects the technicians and pharmacists, who normally mix the chemo compounds. If the drugs come in contact with skin, they can cause burns, and there can be serious health risks for people handling the medications over the long term.

"Chemo is biohazardous," said Stolpman. "You don't want to come in contact with it. You don't want a spill. You don't want it touching your skin because it could cause pretty hefty burns. It's made to kill bad cells, but it sometimes doesn't know the difference."

Riley said Baylor Health System, located in the Dallas/Forth Worth area, also bought the robot and is about two weeks behind the University of Colorado Hospital in deploying it.

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